[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"content-doc-dcio8fbc1d78":3},{"user":4,"document":8,"mainDocument":26,"columnUrl":29,"subscription":30,"footer":42,"text":77},{"isAuthenticated":5,"isAdmin":5,"displayName":6,"avatarUrl":6,"nid":6,"groupLevel":7},false,"",-10,{"id":9,"fullTitle":10,"subTitle":6,"url":11,"columnId":12,"columnName":13,"columnUrl":14,"summary":6,"contentHtml":15,"mainContentHtml":6,"posterUrl":16,"createDate":17,"displayDate":18,"displayDateSlash":19,"pageviews":20,"tags":21,"hidden":5,"isSubContent":5,"replyDocOrTargetId":6,"contentType":22,"videoId":6,"liveVideoUrl":6,"duration":23,"price":23,"priceText":24,"priceBadgeText":24,"priceBadgeClass":25,"freeForMinGroupLevel":23,"redirectUrl":6,"readyToStream":5},"dcio8fbc1d78","礼来(LLY)备战口服减肥药市场！建立充足库存以待FDA批准","\u002Fdoc\u002Fdcio8fbc1d78","col18178739ee","美股资讯","\u002Fcol\u002Fcol18178739ee","\u003Cp> \u003C\u002Fp>\r\n\u003Cp>\u003Cspan style=\"font-size: large;\">美股投资网获悉，根据一份监管文件显示，制药巨头礼来(LLY)已为其实验性减重口服药orforglipron建立库存，正等待未来数月内美国食品药品监督管理局(FDA)可能对该口服GLP-1药物作出的批准决定。\u003C\u002Fspan>\u003C\u002Fp>\r\n\u003Cp>\u003Cspan style=\"font-size: large;\">在周四提交的10-K年报文件中，该公司记录，截至2025年12月31日，与orforglipron相关的主要为上市前库存金额为15亿美元，而一年前为5.481亿美元。礼来首席医疗官今年1月曾表示，一旦FDA批准这款每日一次服用的药片，公司已具备足够的orforglipron供应以满足预期需求。\u003C\u002Fspan>\u003C\u002Fp>\r\n\u003Cp>\u003Cspan style=\"font-size: large;\">礼来旗实验性减重口服药下orforglipron获得美国国家优先审评凭证。目前，该药物有望在2026年第二季度获得美国监管批准，作为肥胖或超重成年人的口服治疗选择。其竞争对手诺和诺德(NVO)已在口服减重药市场取得先发优势。上个月，这家丹麦制药商为美国自费客户推出了其Wegovy药片版本。\u003C\u002Fspan>\u003C\u002Fp>\r\n\u003Cp>\u003Cspan style=\"font-size: large;\">礼来在去年6月公布了其口服小分子GLP-1类药物orforglipron在三期临床试验ACHIEVE-1中的详细数据。数据显示，在所有剂量组中，这款在研药物实现了2型糖尿病成人患者糖化血红蛋白平均1.3%至1.6%的降幅，且在用药四周内就可观察到改善，同时，高剂量组在第40周时实现平均体重减轻近8%。\u003C\u002Fspan>\u003C\u002Fp>\r\n\u003Cp>\u003Cspan style=\"font-size: large;\">据悉，在试验中，orforglipron被每日一次服用，剂量为3毫克、12毫克和36毫克。结果显示，只有12毫克和36毫克剂量组在体重减轻方面相较于安慰剂显示出具有临床意义且统计显著的效果。此外，礼来指出，orforglipron的安全性表现与GLP-1药物类别的既往耐受性数据一致，胃肠道不适为报告频率最高的不良事件。\u003C\u002Fspan>\u003C\u002Fp>\r\n\u003Cp>\u003Cspan style=\"font-size: large;\">值得一提的是，周四有报道称，诺和诺德计划加大在爱尔兰的投资，在当地生产其畅销减肥药Wegovy的口服版本，以供应美国以外的市场。诺和诺德首席执行官迈克·杜斯达尔表示，诺和诺德将扩建其位于爱尔兰中部阿斯隆(Athlone)的生产设施。但他拒绝透露投资规模。\u003C\u002Fspan>\u003C\u002Fp>\r\n\u003Cp>\u003Cspan style=\"font-size: large;\">杜斯达尔称，Wegovy口服药于1月初上市，成为有史以来最成功的药品首发之一，目前已有超过24万名美国患者服用。诺和诺德目前在美国本土生产供应美国市场的减肥药口服版本。尽管减肥药市场的价格战正在加剧，但诺和诺德希望，这款口服药将成为其重夺曾经主导的减肥市场的重要武器，并弥补与竞争对手礼来之间的差距。\u003C\u002Fspan>\u003C\u002Fp>\r\n\u003Cp>\u003Cspan style=\"font-size: large;\">最专业的美股资讯推荐美股大数据 \u003Ca href=\"https:\u002F\u002FStockwe.com\u002F\">https:\u002F\u002FStockwe.com\u002F\u003C\u002Fa>\u003C\u002Fspan>\u003C\u002Fp>\r\n\u003Cp>\u003Cspan style=\"font-size: large;\">如何识别美股市场异常波动？美国机构主力资金买卖情况，出货和吸筹，使用美股投资网VIP会员，2008年成立于美国硅谷，由前纽约证券交易所分析师Ken创立，联合多位摩根斯坦利分析师，谷歌 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buy@TradesMax.com 美国电话 626-378-3637","公司介绍","\u003Cp class=\"MsoNormal\">美股大数据 StockWe.com 是一个美国领先的金融和美股信息大数据提供商，紧盯华尔街金融市场和行情，2008年成立于美国硅谷，创始人是前纽约证券交易所资深分析师Ken，联合多位摩根斯坦利分析师，谷歌 Meta工程师利用AI和大数据，配合十多年美股实战经验和业内量化交易模型，每天处理千万级股票数据：挖掘潜力大牛股，捕捉期权异动大单，实时主力资金流向、机构持仓变化、川普突发新闻，精准买卖信号第一时间发到您手机APP。\u003C\u002Fp>","专业美股投资者都在这里",{"loading":78,"search":79,"searchPlaceholder":79,"hotContent":80,"draft":81,"noData":82,"searchNoData":83,"edit":84,"editVideo":85,"courseContent":86,"more":87,"buyNow":88,"subscribeNow":89,"encoding":90,"paidContent":91},"Loading...","搜索","热门内容","草稿","目前没有任何内容公布","当前检索内容没有数据","编辑","编辑视频","课程内容","更多","立即购买后观看","- 立即订阅 -","视频编码中...","付费内容"]